Why are polygenic diseases less suited to gene therapy?

Answers

Answer 1

Answer:

Polygenic therapies are more likely to show unintended effects in other regions of the genome likely resulting in harmful diseases.

Explanation:

Gene therapy involves biotechnological techniques that add or remove gene sequences in the genome. These are typically used in eliminating harmful genes that cause genetic diseases or disorders and are generally thought to improve an individual's quality of life.

Polygenic traits are controlled by several genes. Similarly, polygenic diseases may be caused by variations in several gene sequences. These include hypertension, heart disease, and diabetes. Polygenic therapies are more likely to show unintended effects in other regions of the genome, leading to other deleterious disease-causing effects.

Why Are Polygenic Diseases Less Suited To Gene Therapy?

Related Questions

Question 2 of 10
The triangles shown below must be congruent.
601
81
A. True
B. False

Answers

Answer:

81

Explanation:

the answer will be 319

False I believe since they aren't the same length

The respiratory system accounts for what percentage of the total water loss in the body?
5 to 10 percent
10 to 20 percent
35 to 50 percent
50 to 75 percent

Answers

Answer:

B. 10 to 20

Explanation:

Edge

Answer:

I believe its B. 10 to 20 percent

Explanation:

hope this helps

Can someone help?? Idk why but I can't figure out what I'm doing wrong

Answers

Answer:

1. Okay, so Chaz should have ee (correct) and Be should actually have Ee (heterozygous means mix). So it should equate to:

Ee, Ee, ee, ee. so 50% and 50% phenotype for normal eyes and heart eyes.

      e   |   e___

E |  Ee  |   Ee      |

____________|

e |   ee |  ee       |

____________|

Why is it important to maintain balance in the environment?

Answers

Answer:

so that the food chain won break and we all don die

:)

Explanation:

Explanation:

Because it effect ecosystem

Pollution will increase

Effect in atmosphere

Decrease natural beauty

To produce starch, glucose molecules bond together through

Answers

This is what I got hope it helps

Chemical Reaction

Reproduction

its biology, help please :)​

Answers

For question 3, it would not leak through the whole sandwich because the cell membrane is thick

What is fermentation ?
?​

Answers

Answer:

Fermentation is the process in which a substance breaks down into a simpler substance.

Answer:

A chemical breakdown of a substance.

Explanation:

An example would be yeast and bacteria. :))

DNA is the molecule that stores ____ information and directs the production of _____ that makes cells unique and suited to their functions

Answers

The answer is Genetic, proteins
Genetic, and proteins !!

what are three human activities have transformed the biosphere? ​

Answers

Answer:

Agriculture, Development, and Industrial growth.

Explanation:

Answer:

Agriculture, Development, and Industrial growth.

the diagram below represents part of the ribcage.
Name parts labeled W, Y and Z.​

Answers

Answer:

where is the diagram

Explanation:

What shape is a cuttlefish’s pupils?

Answers

Answer:

The eyes of cuttlefish have modified horizontal slit-pupils with a distinctive W shape in the bright light, but in darkness the pupil is the shape of a circle. Two suggestions have previously been made for a function of the W-shape: (1) camouflaging the eye; (2) providing distance information.

Explanation:

Is this the correct answer smart people tell me the correct answer pls

Answers

Do you have a picture?

Answer:

It is A

Explanation:

how does a change in concentration influence the diffusion of perfume

Answers

Answer:

Diffusion. Molecules are in constant motion and tend to move from regions where they are in higher concentration to regions where they are less concentrated. ... An example of diffusion in gases occurs when a bottle of perfume is opened at the front of a room.

Some proteins, like Response area, have the function of Response area. Nucleic Acids, like Response area, are responsible for Response area. Carbohydrates provide Response area for cells, and Response area is a common carbohydrate. Lipids are used as Response area, and a Response area is an example of a lipid.

Answers

Answer:

lool

Explanation:

lol wassup daysi its me roeen

i was tryna see the same question for school

Will Award 100 points and will award brainliest answer
A medical researcher is trying to develop a diagnostic technique for a disease which is characterized by the misexpression of a large number of unrelated genes. What would be the most appropriate technique?
A. Gene chip
B. Genome sequencing
C. White blood cell count
is the answer c?

Answers

Answer:After you have listened to each music selection and filled out the listening chart for each, it’s time to do some comparing and contrasting.

Write a one- to three-paragraph essay that compares and contrasts the two pieces of music that you listened to. If you need some help with what specific things to compare/contrast, refer to the listening charts that you filled out or the questions below:

How do the two musical pieces differ?

How are the two musical pieces similar?

Were the instruments featured in the two pieces different from each other?

What differences or similarities were there in tempo, or speed, of the music?

Were there any differences in what you were imagining as you listened to each piece? Did you hear a story in either piece? What emotions were evoked from listening to each song?

For information on how you will be graded, please refer to the rubric below.After you have listened to each music selection and filled out the listening chart for each, it’s time to do some comparing and contrasting.

Write a one- to three-paragraph essay that compares and contrasts the two pieces of music that you listened to. If you need some help with what specific things to compare/contrast, refer to the listening charts that you filled out or the questions below:

How do the two musical pieces differ?

How are the two musical pieces similar?

Were the instruments featured in the two pieces different from each other?

What differences or similarities were there in tempo, or speed, of the music?

Were there any differences in what you were imagining as you listened to each piece? Did you hear a story in either piece? What emotions were evoked from listening to each song?

For information on how you will be graded, please refer to the rubric below.

Write a one- to three-paragraph essay that compares and contrasts the two pieces of music that you listened to. If you need some help with what specific things to compare/contrast, refer to the listening charts that you filled out or the questions below:

How do the two musical pieces differ?

How are the two musical pieces similar?

Were the instruments featured in the two pieces different from each other?

What differences or similarities were there in tempo, or speed, of the music?

Were there any differences in what you were imagining as you listened to each piece? Did you hear a story in either piece? What emotions were evoked from listening to each song?

For information on how you will be graded, please refer to the rubric below.

Explanation:

Answer

Explanation:

ummmmmmmmmmmmmmmmmmmmm oh i unber stand it now

c is yo answer

help please ! TYSM!!!

Answers

Answer:

Most likely A

Explanation:

As the height (m) increases, the weight (kg) also tends to increase.

help asap its either a c or d​

Answers

Answer:

A) Simple Diffusion

Explanation:

Facilitated diffusion has a protein channel, while simple does not. If its not A, then its definitely D, no doubt

what is the goal of seed dispersal? 10 points
A. to help plants grow more quickly
B. to have new plants that grow far away from parent plants so that they dont compete for resources
C. to spread different species of plants to different parts of the world
D. to spread seed evenly to a given area

Answers

Answer:

B. to have new plants that grow far away from parent plants so that they dont compete for resources

Explanation:

Complete the sentence to explain how body parts move.

When muscles contract and relax, the muscles move the
attached to them. This results in movement of different parts of the body.

Answers

The answer to the question is Bones

Answer:

Bones

Explanation:

did the test

What two groups are represented in archaeopteryx?

Please help

Answers

Answer:

The species of Archaeopteryx is lithographica and siemensii

Explanation:

Fun fact: Archaeopteryx is a combination of two ancient Greek words: archaīos, meaning "ancient," and ptéryx, meaning "feather" or "wing." 

Archaeopteryx has long been thought to be the earliest known bird and a transitional form between birds and reptiles.

What are Archaeopteryx?

Many consider Archaeopteryx, which lived approximately 150 million years ago, to be the first bird.

It is actually a transitional species between the birds we see in our backyards and predatory dinosaurs like Deinonychus.

Many features of Archaeopteryx, such as teeth and a long tail, indicate that it evolved from comparatively tiny carnivorous dinosaurs.

It also has a wishbone, a breastbone, hollow thin-walled bones, air sacs in the backbones, and feathers, as do nonavian coelurosaurian relatives of birds.

Archaeopteryx was thought to be the first recognized bird and a transitional form between birds and reptiles for a long time.

Thus, the two groups that are represented in archaeopteryx are birds and reptiles.

For more details regarding archaeopteryx, visit:

https://brainly.com/question/15828307

#SPJ2

Need help with this

Answers

Answer:

Respiratory Sir

Explanation:

Why is protein synthesis different in prokaryotes and eukaryotes

Answers

Answer:

A few aspects of protein synthesis are actually less complex in eukaryotes. In prokaryotes, mRNA is polycistronic and may carry several genes that are translated to give several proteins. In eukaryotes, each mRNA is monocistronic and carries only a single gene, which is translated into a single protein.

Which of the following factors can limit photosynthesis by being either too high or too low?
a.
Light
c.
Oxygen
b.
Carbon dioxide
d.
Temperature

Answers

Answer: A) Light

Explanation:

Hey!! It's me again because why not!!

Answer:

Temperature

Explanation:

Condensation reactions are also referred to as dehydration synthesis. Explain how dehydration synthesis is descriptive of the process.

Answers

Condensation reactions are also referred to as dehydration synthesis. Explain how the name dehydration synthesis is descriptive of the process.

In the process, a water molecule is released along with energy.



Hope this helps!

I'll mark brainliest please help

Answers

Answer: The food that animals eat can be transformed into usable energy for cells or can be used to build new cells, which form tissues like skin and muscle. ... The process of growth involves eating food, breaking down food through digestion, absorbing nutrients from food, and building tissue.

Hope this is what you are looking for... stay safe and have a great day!!! :D

How does the prophase step play a role in plant growth?

Answers

Answer:

Like other multicellular organisms, plants grow through a combination of cell growth and cell division. Cell growth increases cell size, while cell division (mitosis) increases the number of cells. As plant cells grow, they also become specialized into different cell types through cellular differentiation

Explanation:

PLEASE HELPPP What type of signaling is represented in the figure?

Answers

Answer:

Hormonal

Explanation:

the correct answer shown in the picture is hormonal.

Drag the numbers to put the following steps in the correct order.
42531 is the correct answer i solved it




As electrons move down the ETC, a H+ gradient is made.




The Krebs cycle produces ATP, NADH and CO2.




H+ pass through the ATP synthase to make ATP.




NADH gives electrons to the ETC.




In glycolysis, glucose is split into two pyruvate and makes some ATP.

Answers

Answer:

- In glycolysis, glucose is split into two pyruvate and makes some ATP

- The Krebs cycle produces ATP, NADH and CO2

- NADH gives electrons to the ETC

- As electrons move down the ETC, a H+ gradient is made

- H+ pass through the ATP synthase to make ATP

Explanation:

This question is describing the processes involved in cellular respiration. Cellular respiration is the way through which living cells synthesize energy (ATP) by breaking down sugar. Cellular respiration involves three major steps: glycolysis, Krebs cycle, and oxidative phosphorylation (electron transport chain).

- Glycolysis is the process whereby glucose is broken down into pyruvic acid or pyruvate with the synthesis of net 2 ATP molecules.

- Kreb's cycle produces ATP, NADH and CO2.

- NADH is an electron carrier that donates electrons to the Electron transport chain (ETC).

- Electrons move down the ETC to produce a proton (H+) gradient

- The proton (H+) passes through an enzyme called ATP synthase to make ATP from ADP molecule.

Plz idk if it’s correct

Answers

Answer:

Yes you are correct.

Explanation:

Number one is the rough ER not the nucleus. Number 3 is the mitochondria not the Ribosomes. This is an animal cell so there can not be a cell wall. There are exactly 3 small vacuoles in an animal cell so yes, you are correct.

Answer:

yes

Explanation:

i hope this helps

What type of population growth does the graph show? How do you know?

Answers

Answer:

Logistic growth

Explanation:

The curve has a period of exponential growth, but then levels off at a stable size. growth whose rate becomes ever more rapid in proportion to the growing total number or size.

Other Questions
how do you factor an expression using the gcf Your family is organizing the household chores to get ready for a party and has asked you to write the chores your brother does. Write two (2) complete sentences in Spanish, to describe what he does Use the following suggestions as a guide for your answer:You may copy and paste the accented and special characters from this list if needed: , , , , , , , , , , , , , , .*Note: The sample sentences in parentheses are just a guide to help you form your sentences. You must come up with your own original answers keeping academic integrity intact. In one sentence, write two household chores your brother Mario does inside the house. Remember to use the l form of the verbs. (e.g., Mario cooks pork and sweeps the kitchen.)In one sentence, write at least one chore your brother does outside the house. Remember to use the l form of the verbs. (e.g., He walks the dog.) Suppose you mate a black rooster with a white hen. The feathers of all the offspring are "gray," a color that is intermediate between black and white. Explain the inheritance pattern in these chickens. Write for 5 minutes about one thing for which you are thankful. HELP!Determine whether the equation represents a direct variation. If it does, findthe constant of variation. 5x + 12.5y = 0a. -.4b. NOc. 2.5d. .4 The elements of a group have the same number ofin theirshell.A outerB. electronsc.innerD. protons What do the buildings and the way the village was constructed say about the civilization?? An advantage of using cell models when studying cells is that the cell models- Venezuela's oil production has increased recently and helped their economy becauseof the high demand for oil.TrueFalse how much oxygen is taking in for one process of cellular respiration Select the statements that were true of U.S.-French relations. French involvement changed the nature of the war for the British. France did not become involved at all before Saratoga. French aid was substantial. PLSSS HELP ME PLSSS I WILL MARK U!!!!Direction: Watch the video and answer the questions below Describe and create Mr. Bittering's character at the beginning, middle, and end of the story using cliparts and/or Google images. The written description should include a detailed description of his physical traits as well as his emotional traits. It should also include details from the story about how he reacts or responds to his environment. Sentences must be written in the 7up method (7 words or more) must include at least 5-7 sentences.Please help this is due Friday!!!!!!! WILL MARK BRAINLIESTThis is from Dark They Were story!PLEASEEEEEE HELP. Brandon used 1 23 kg of plant food on his strawberry plants and used 14kg for his tomato plants.He wants to feed his strawberry plants 2 more times and his tomato plants one more time.How much plant food will he need? most poisonous alkaloid is extracted from tobacco leaf and widely used as an insecticide Decide whether each plot event is likely to occur in the beginning, the middle, or the end of a story. The main character lives happily ever after. The main character explains where he or she lives. The main character questions another character about why he or she acted in a certain way. prove that 1 + cos 2A / sin 2A=CotA Which is example of a greek or latin root who is the current pres-elect of united states How do I factor this?