what is the mechanism of action of grapiprant?

Answers

Answer 1

Answer:

Grapiprant has been accepted very greatly in veterinary as its mechanism of action is a targeted approach to pain management by not having any interaction with the production of prostanoids and thus, by not interacting with other prostaglandin receptor pathways

Answer 2

Grapiprant, also known as AT- 001 and CJ- 023, is a medicine from the piprant class.

These motes were deduced from acyl sulfonamide and are characterized to be a new series of para N-acyl amino methyl benzoic acid known to be prostaglandin receptor antagonists. This type of motes is presently in development for veterinary cases. This class of medicines as defined in 2013 by the World Health Organization. Grapiprant has been approved in March 2016 by the FDA's Center for Veterinary Medicine as anon-cyclooxygenase inhibiting NSAID for veterinary use.

mechanism of action of grapiprant-

Grapiprant is an EP4 prostaglandin receptor antagonist and therefore the exertion of this medicine is allowed to be fully related to the picky leaguer of this receptor.1 It binds to mortal and other mammals' EP4 prostaglandin receptor with high affinity without snooping with other prostaglandin pathways which are important for a variety of physiological functions. The list of laropiprant blocks the PGE2 list and hence its natural effect related to the signaling pain and inflammation waterfall.Grapiprant has been accepted veritably greatly in veterinary as its medium of action is a targeted approach to pain operation by not having any commerce with the product of prostanoids and therefore, by not interacting with other prostaglandin receptor pathways.

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Related Questions

Prescription medications prescribed to relieve pain and include the illegal?
drug heroin
O Inhalants
Opioids
Depressants
Cannabinoids

Answers

Answer:

Opioids

Opioids are a class of drugs that include the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription

Which items should you refrigerate or freeze after 2 hours?
A) perishables
B) prepared food
C) leftovers
D) all of the above

Answers

Answer:

D) All of the above.

Explanation:

You should refrigerate perishables, prepared food, and leftovers after 2 hours because when left out they will spoil fast.

Hope this helps!

If not, I am sorry.

As the liquid substance moves through the more and more water gets extracted so that is becomes a more semi-solid substance called feces. A. colon B. rectum C. small intestine ​

Answers

I believe its A correct me if im wrong

i hope someone can help me here please don't answer nonsense!​

Answers

Answer:

This is only an example of a poster that I had previously done.

Explanation:

Use your career ideas :)

Hope this helps you just to get started...

There were HIPAA violations around PHI data security, storage and handling identified in the file servers of the administrative building. Identify an administrative control to remediate the HIPAA violations.

Answers

Administrative control to remediate the HIPAA violations are:

Data Encryption Rigorous Firewall and Antivirus. Cybersecurity Awareness Training.

How can Administrative control to remediate the HIPAA violations?

Administrative control that can be used in savaging the HIPAA violations, includes the Data Encryption  which will help to protect some of the data from been attacked.

Cybersecurity Awareness Training can as well be done this will help to educate people and to avoid violation.

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what is circulatory system​

Answers

Answer:

The circulatory system is the system that circulates blood and lymph through the body, consisting of the heart, blood vessels, blood, lymph, and the lymphatic vessels and glands. Also called cardiovascular system.

Answer:

The human circulatory system consists of a network of arteries, veins and capillaries, with the heart pumping blood through it. It is also responsible for collecting metabolic waste and toxins from the cells and tissues to be purified or expelled from the body

We can tell whether a person is having an eating disorder just by looking at the weight. If a person’s weight is between a healthy range, he/she will never have an eating disorder. Are the above statements true or false?

Answers

Answer:

false

Explanation:

Answer:

False

Explanation:

You would have to diagnose them for an eating disorder- people can just be naturally petite. That does not mean they have an eating disorder. I hope this helps! :) Have a great day ^^

A private school might be the best option for which of the following students?

Jake, who excels at math and science, enjoys challenges, and thrives in a social environment with his peers; his family has their own transportation to and from school for him.
Kat, who has a hard time with the daily school routine and prefers to do most of her studying later in the day.; her parents also prefer to make their own decisions about her curriculum.
Nicoletta, whose family is Catholic and who values religious principles and wants them included in her education; her family has money to pay for tuition each month if needed.
Trevon, who is quiet, introverted, self-motivated, and inspired by hands-on and experiential learning; his family does not have tuition money or transportation to and from school for him.

Answers

Answer:

Kat

Explanation:

Trevon, who is quiet, introverted, self-motivated, and inspired by hands-on and experiential learning; his family does not have tuition money or transportation to and from school for him.

A private school might be the best option for Trevon. Private schools often offer smaller class sizes, which can be beneficial for introverted students like Trevon who may prefer a quieter and more personalized learning environment. Private schools may also have more flexibility in their curriculum, allowing for hands-on and experiential learning opportunities that can better cater to Trevon's learning style.

Furthermore, private schools can provide a strong sense of community and support, which can be valuable for self-motivated students like Trevon. He may thrive in an environment where he can form meaningful connections with teachers and classmates.

However, it's important to consider Trevon's family's financial situation. If they cannot afford the tuition fees, it may not be a feasible option for him. In such cases, seeking out scholarships or financial aid opportunities at private schools could be explored. Alternatively, Trevon's family may need to consider other educational options that align with their budget and transportation limitations, such as public schools with specialized programs or homeschooling with hands-on learning opportunities. The priority should be finding an educational setting that supports Trevon's learning preferences and needs while also taking into account his family's practical circumstances.

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What is the appropriate osha standard for hazard communication?.

Answers

Answer:

OSHA 's Hazard Communication Standard . Standard Number: 1910.1200 OSHA requirements are set by statute, standards and regulations.

Explanation:

I hope this helps let me know if it does not

What is a side effect of Halothane?

Answers

One of the side effects of Halothane is that it causes hepatotoxicity.

What is hepatotoxicity?

Hepatotoxicity is also referred to as toxic hepatitis and it can be defined as a type of toxic liver disease that causes damage to the liver, especially due to an exposure to xenobiotics and substances such as:

ChemicalsHerbsDrugsFood additivesAlcohol

Based on medical information and health records, one of the side effects of Halothane is that it causes hepatotoxicity.

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You are alone and have identified a child who is not responsive. You have performed chest compressions for 2 minutes. What is the next step in CPR?
A. Try to find a pulse.
B. Call 911.
C. Continue chest compressions.
D. Go get help

Answers

B.

Call 911

Explantation:

when the client has increased difficulty breathing when lying flat, the nurse records that the client is demonstrating:

Answers

When the client has increased difficulty breathing when lying flat, the nurse records that the client is demonstrating Orthopnea.

What is orthopnea?

Orthopnea is shortness of breath or difficulty breathing when you're lying down.

This discomfort when breathing while lying down flat is common in people with some types of heart or lung conditions.

Thus, when the client has increased difficulty breathing when lying flat, the nurse records that the client is demonstrating Orthopnea.

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Why should you change up your exercise routine? so your body does not get bored if you repeat the same exercise, the body works more efficiently and burns less calories. if you repeat the same exercise, the body works more efficiently and burns more calories to experience different types of exercise.

Answers

Answer:

if you repeat the same exercise, the body works more efficiently and burns more calories to experience different types of exercise.

Explanation:

option 3

________ are fleeting, low-intensity events that influence our conscious thinking and behavior without our awareness.

Answers

Answer:

Characteristics of emotions

Characteristics of emotions are fleeting, low-intensity events that influence our conscious thinking and behavior without our awareness.

What are emotions according to psychology?

For this science, emotion is a mental and physiological state that is linked to a variety of feelings, thoughts and ways of acting. For example, an emotion manifests itself subjectively through affects.

In this case, the emotions are very useful information, as they act as a kind of “internal radar”, allowing us to know how we are feeling in the present moment.

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Tyler knows that healthy eating and exercise go together so he is trying to eat as little as possible. However, he is exercising quite a bit and finds that he is hungry all the time. What is the BEST advice for Tyler?

If he drinks a lot of water he will be less hungry and not mind as much.

It takes a lot of effort to be healthy, and he should not expect it to be easy.

His body will need more energy because he is exercising so he should eat more.

Being hungry is just part of the process of getting healthy, and he’ll get used to it.

Answers

Answer:

His body will need more energy because he is exercising so he should eat more.

Explanation:

I would say that this is the best answer for this question. When you work out, you should take in more calories than you burn... That's what I do and it works... calories are the main thing that keeps us going. Also, drinking a lot of water would be a great idea for when you're working out.

How can you best avoid nutrient deficiencies?
A. Avoid colorful foods.
B. Avoid home-cooked meals in favor of restaurant food.
C. Eat a variety of fresh foods within each food group.
D. Eat a variety of snacks and desserts.

Answers

Answer:

the answer is C.

Explanation:

All the other options would give you higher chances of nutrient deficiencies.

Which item is likely to be the most useful to Jorge right
now?
O blanket
O flare
O whistle
O map of the area

Answers

Jorge would want a whistle because he would want people to hear him to know where he is

Which is a long-term consequence of an injury?

a few missed days from work or school
the need for physical therapy and rehabilitation
some temporary discomfort at the injury site
a visit to the emergency room right after the injury

Answers

The need for physical therapy and rehabilitation
Answer:

The need for physical therapy and rehabilitation

Explanation:

An injury is caused by damage suffered in some part of the body, if it is not treated on time and properly, it can trigger long-term problems such as the need to resort to physical therapy or rehabilitation to recover mobility and functionality, in the part of the body that suffered the injury.

The physical therapy sessions are carried out by a professional who designs exercises oriented according to each case to recover mobility in the parts of the body affected by the injury and to help the total recovery of the individual.

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sarah decided go drink less juice. she read current dietary guidelines about daily water intake. which steps in making smart food choices did sarah follow? select three options

Answers

What are the options?

oxygen toxicity is a condition in which:

Answers

Answer:

gas: because oxygen is gas

Oxygen toxicity is lung damage that happens from breathing in too much extra (supplemental) oxygen.

13. The first step in handling stress is
A. removing all stressors from your environment.
B. becoming aware of your own
reaction to it.
• C. trying to relax through meditation techniques.
• D. catching up on missed sleep.

Answers

Answer: A. Removing all stressors from your environment

Explanation:

an adult patient suffers cardiac arrest in bed and requires cpr. when compressing the patient’s chest, which technique promotes high-quality cpr?

Answers

The technique that promotes high-quality CPR is:

Compressing with the straight up and down movement of the hands.

What is CPR?

CPR is short for cardiopulmonary resuscitation. This first aid care is often given to maintain a steady flow of oxygen when a person has lost consciousness.

The best form of chest compression to give a cardiac arrest patient will be interlacing the two hands and closing up the elbows as the chest is compressed.

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why should we do light exercise?​

Answers

Answer:

30 Minutes Of Light Exercise Can Benefit Health A lot

It Helps In blood Circulation....

Explanation:

Hope It Helps!!!

Answer:

Light exercises like slow walking, gardening or even dusting not only lowers the risk of cardiovascular diseases but improves strength, lowers blood pressure or (hypertension), lowers stress, helps in maintaing an ideal weight.

All in all, light exercises helps in maintaining a quality life with improved health and mental well being.

Hope it helps!

a 78-year-old patient who had knee replacement surgery 2 days ago goes into cardiac arrest. which underlying cause should be given priority consideration?

Answers

Anemia should be given priority consideration as the underlying cause of the cardiac arrest.

What is Anemia?

This refers to the condition in which there is insufficient red blood cells in the distribution of oxygen to parts of the body.

This leads to catecholamine being released which results in high heart rate and in severe cases cardiac arrest.

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During prerace, an athlete who weighs 70 kg would need between _____ and _____ g of carbohydrate daily.

Answers

Answer: between 490 and 910 g

Answer:

490, 910

Explanation:

are sunglasses allowed at school on really hot UV rays and days

Answers

The need for pupils to be protected from sun exposure in schools is so critical that the California legislature took the time to establish a law giving students the legal right to bring sunscreen and wear sun-protective apparel to school.

What are sunglasses?

Sunglasses, often known as sun glasses, are a type of protective eyewear meant to shield the eyes from strong sunshine and high-energy visible light.

When heading to PE, recess, or drop off/pick up, children are allowed to wear sunglasses and hats to protect themselves from the sun. Hats and sunglasses are only permitted outside the building, according to the Dress Code. At no point are flip flops permitted. If they wear sandals to school, children are encouraged to bring tennis shoes to PE. When the child's arm is down at his or her side, the hemlines of shorts and skirts must not be higher than the child's fingertips.

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What is contraindicated in suspected basal skull fracture?

Answers

Nasopharyngeal airway is usually contraindicated in suspected basal skull fracture.

What is a basal skull fracture?

A basal skull fracture is also referred to as skull base fracture and it can be defined as a type of traumatic head injury that generally involves a break in one of the bones located at the base of the skull.

In Medicine, nasopharyngeal airway is usually contraindicated in suspected basal skull fracture in order to secure an open airway.

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A prescription for ibuprofen 800mg was faxed in with a sig of 1 tid prn ha. what does ha stand for?

Answers

HA stands for Headache in this case

HA is an abbreviation used in the pharmaceutical world during prescription of drugs.

Ibuprofen is a drug prescribed mainly for pain relieve, headache, chills, fever, etc.

Therefore, HA stands for Headache in this case.

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With the use/abuse of alcohol, there is a buildup of fatty tissues in the heart muscle
true
false

Answers

Answer:

the answer is true there is a buildup of fatty tissues in the heart muscle

a client with a discoid facial rash caused by systemic lupus erythematosus (sle) asks why a urine sample is needed. which response will the nurse make to the client?

Answers

A client with a discoid facial rash caused by systemic lupus erythematosus (sle) asks why a urine sample is needed. The best response to be given to the patient is: the rash is related to an se.xually transmitted disease.


What is Discoid Facial Rash?

Discoid Facial Rash is a kind of sore that develops on the face or on the scalp. It does not itch or hurt, but is usually transmitted se.xually.

Hence, the nurse may asked the patient if they have been se.xually active lately.

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