prostate cells usually require testosterone and other androgens to survive. but some prostate cancer cells thrive despite treatments that eliminate androgens. one hypothesis is that estrogen, often considered a female, may be activating genes normally controlled by an androgen in these cancer cells. desribe one or more experiments to test this hypothesis

Answers

Answer 1

One can check for the translation and transcription of genes of interest in the absence of androgens, one can check whether the estrogen is involved in the expression of oncogenic proteins of interest by depleting the estrogen, and one can also examine the existence of estrogen receptor complex in the prostrate cancer cells nuclei.  

• One can check for the translation and transcription of genes of interest in the non-existence of androgens and if these genes are expressed then this suggests that apart from androgens other factors also affect their expression.  

• One can deplete the estrogen from cancer cells and if the involvement of estrogen is there in the expression of oncogenic proteins of interest then its reduction will result in diminished multiplication rates in cancer cells.  

• One can also test the existence of estrogen-receptor complex in the prostate cancer cells nuclei to confirm that estrogen is taking part in the regulation of gene expression.  

Thus, various experiments can be conducted to check that whether the expression of genes controlled by the androgens under normal conditions are affected by the presence of estrogens in prostate cancer cells.  

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Related Questions

all life would come to an end if there are no green plants.
Explain

Answers

Answer:

So if there were no green plants, no food will be available for the other living organisms. ... During respiration, organisms use this oxygen for releasing energy. Without these 2 important aspects of food and oxygen, it would be difficult for life to survive on earth.

Explanation:

What are the structural differences between a cockroach and a grasshopper? ​

Answers

Cockroaches have legs for crawling on walls and ceilings, but grasshoppers have legs for jumping. Some cockroaches have wings for flying, but most others don't. Grasshoppers have wings for making a sound, whether it's to attract a mate or to just be annoying. Grasshoppers have a body that is split into multiple segments (more than just one), while cockroaches have only like 2 body segments. Cockroaches have barbs on their legs for a sense of touch, while grasshoppers don't. The legs of a cockroach are very sensitive though. Cockroaches can survive a nuclear explosions because the rads don't affect them. But the heat from the nuclear blast will certainly kill a human, as well as a cockroach if exposed. Obviously, grasshoppers couldn't survive a nuclear explosion. The only down side to roaches surviving a nuclear explosion is them turning into radroaches, like in the Fallout game series from the game developing company, Bethesda Game Studios! If there were a nuclear explosion, then the roaches would mutate into human head sized roaches that can actually attack a human! (this is just a theory, not scientifically proven, lol)

I hope this helps you even a little bit, have a great day.

The difference of this is that the cockroach has a wing and can fly while the grasshopper does'nt have a wing but it can jump high. Grasshoppers are found in the grass & the cockroaches are found in a dirty places.

Also, Cockroach are found in dirty place while grasshopper are found on the grass.

It is said that it is the male who determines the sex of the baby rather than it is the female. From your knowledge of the sex chromosome, is it true?

Answers

Answer: yes because they have xy chromasomes so they have to give one of them

Explanation:

What’s one indirect consequences of building Seawalls

Answers

The shoreline habitat is destroyed through loss of sand. -is one indirect consequence of building seawalls. The shoreline habitat is destroyed through loss of sand.

Answer:

The shoreline Habitat is destroyed through loss of sand.

Explanation:

Humans should consider microbes as beneficial organisms for all of the following reasons except:
Group of answer choices

they purify water in the hydrosphere.

they consume carbon dioxide during photosynthesis.

they decompose organic waste in the geosphere.

they generate oxygen in the hydrosphere.

they filter ultraviolet radiation in the atmosphere.

Answers

Answer:

they purify water in the hydrosphere

Microbes are beneficial as well as detrimental to the environment. They do not purify water in the hydrosphere instead pollute them. Option (A) is correct.

How does microbes affect water quality ?

The quantity and variety of native microorganisms in an aquatic environment have a significant impact on water quality .

Physical, biological, and chemical contaminants from human activity can build up in aquatic systems and have significant ecological effects that can be detrimental in nature.

Microbial activity in the aquifer may have an impact on a number of ground-water quality indices, including pH, oxidation/reduction (redox) status, dissolved oxygen, or the presence of certain mineral components. This is especially true if there are elements in the aquifer that bacteria may use to flourish.

Therefore, option (A) is correct option.

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is x male or female in cell reference

Answers

Answer:

An XY chromosome will be a male chromosome pair.

An XX chromosomes will be a female chromosome pair.

Hi i need help with this, it shouldnt be too hard.


Describe the difference between gene mutations and chromosomal mutations, including:

- What are they?

- How do they occur, including their types?

- When will they result in a change in the phenotype of offspring?

Answers

Explanation:

Genetic alternations include chromosomal abnormalities and gene mutations. Chromosomal abnormalities generally arise during cell division. ... Gene mutations are permanent changes in DNA gene sequence. They can arise during normal DNA replication or in response to environmental factors.

Answer:

When a gene mutation occurs, the nucleotides are in the wrong order which means the coded instructions are wrong and faulty proteins are made or control switches are changed. The body can't function as it should. Mutations can be inherited from one or both parents. They are present in the egg and/ or sperm cells.

What type of mutation can affect offspring?

The only mutations that matter to large-scale evolution are those that can be passed on to offspring. These occur in reproductive cells like eggs and sperm and are called germ line mutations. No change occurs in phenotype. Some mutations don't have any noticeable effect on the phenotype of an organism.

A researcher in 2024 studies the evolutionary relationships between influenza viruses by comparing the genomic sequences of the viruses found in pigs, ducks, and humans in a given year. When evaluating the viruses that had infected these hosts the previous year, she identifies a cross-species transfer from pigs to ducks in the year 2022. What information supports the hypothesis that cross-species transfer leads to more severe disease in the new host

Answers

Answer:

pigs suffered severe influenza in the year 2022  

Explanation:

Influenza, commonly known as flu, is a viral infectious disease caused by different types of influenza viruses. Some of the most common symptoms of this disease include, among others, headache, coughing, fever, muscle pain, etc. Influenza viruses can affect humans and different animals such as, for example, cats, dogs, birds and horses. There is evidence showing cross-species influenza virus transmission. For example, it has been shown that the influenza type A virus can be transmitted from one species to another (for example, between humans and pigs). In these cases, cross-species transmission information may indicate how much potential a virus has to cause a pandemic in the new host by analyzing the severity and infectivity of the virus in the original host.

The number of protons plus neutrons in an atom, represented as an average of all naturally occurring forms of the element, is known as_____

Answers

It would be the atomic mass because protons and neutrons and both located inside the atom. Therefore it would equal the mass.

Sparrows produce an average of 5 eggs in each clutch. If there are more than 5. Parents can't adequately feed the young. if there are fewer. Predators may destroy the entire clutch. Which type of selection is this

Answers

Answer:  it would be natural selection

Explanation:

What is a tumor? *
a mass of cancer cells
O a defective p53 gene
An accumulation of cyclins
O the rapidly dividing cells found at the site of a wound

Answers

Answer:

i think it is.. a mass of cancer cells

Explanation:

White flower color is recessive to purple flower color in pea plants. If a pea plant has white flowers, what is
the genotype and phenotype of the pea plant

Answers

Answer:

An organism's genotype is its specific combination of alleles for a given gene. So, for example, in the pea plants above, the possible genotypes for the flower-color gene were red-red, red-white, and white-white. The phenotype is the physical manifestation of an organism's allelic combination (genotype).

Explanation:

hope this helps sorry if it doesn't have a good rest of your night :) ❤

The genotype and phenotype of the pea plant - pp - white flower

According to Mendel, there are two or more alleles (normally two) are responsible for the expression of a trait encoded by the gene.

One allele of the particular gene has the ability to mask the phenotypic expression of the other if present in a genotype together.The allele that masks another is called the dominant allele while the allele being masked is the recessive allele.The recessive allele express their effect only if they are present with the same allele in the genotypeIn this case, a gene that codes for flower color in pea plants is involved.The purple allele (P) is dominant over the white allele (p).It is given that the pea plant has white flower color that is a recessive allele therefore, it is clear that it has two recessive alleles p in its genotype.

Thus, the genotype and phenotype of the pea plant - pp - white flower

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In prokaryotes, certain proteins act to regulate genes by binding to DNA. What could be the effect of these binding proteins?

Answers

Answer:

increase/reduced transcription of those genes

Explanation:

protein binds  either  allowing or preventing transcription

The green machines within a plant are the blank.
Lysosomes chloroplasts mitochondria

Answers

The green machines within a plant are the blank.
chloroplasts are the green machines

You are trying to find which wavelength of light would allow algae to do photosynthesis the worst (you want to prevent algal growth in your pond). Describe your experiment setup:

hypothesis (1 point)

independent variable (1 point - you can choose anything)

dependent variable (1 point) and how you will measure the dependent variable (1 point)

variables you will keep constant (1 point)

Answers

Answer:

The light reactions of many algae differ from those of land plants because some of them use different pigments to harvest light. Chlorophylls absorb primarily blue and red light, whereas carotenoids absorb primarily blue and green light, and phycobiliproteins absorb primarily blue or red light. Since the amount of light absorbed depends upon the pigment composition and concentration found in the alga, some algae absorb more light at a given wavelength, and therefore, potentially, those algae can convert more light energy of that wavelength to chemical energy via photosynthesis. All algae use chlorophyll a to collect photosynthetically active light. Green algae and euglenophytes also use chlorophyll b. In addition to chlorophyll a, the remaining algae also use various combinations of other chlorophylls, chlorophyllides, carotenoids, and phycobiliproteins to collect additional light from wavelengths of the spectrum not absorbed by chlorophyll a or b. The chromophyte algae, dinoflagellates, cryptomonads (class Cryptophyceae), and the class Micromonadophyceae, for example, also use chlorophyllides. (Chlorophyllides, often incorrectly called chlorophylls, differ from true chlorophylls in that they lack the long, fat-soluble phytol tail that is characteristic of chlorophylls.) Some green algae use carotenoids for harvesting photosynthetically active light, but the Dinophyceae and chromophyte algae almost always use carotenoids. Phycobiliproteins, which appear either blue (phycocyanins) or red (phycoerythrins), are found in red algae and cryptomonads.

Explanation:

sana makatulong

Which of the following is a characteristic of the plasma membrane? It is made up of one layer of phospholipids. It doesn't contain any molecules aside from phospholipids. The outward-facing phospholipid tails give it a rough quality. It allows some molecules to pass through but prevents others from doing so.

Answers

Answer:

It allows some molecules to pass through but prevents others from doing so.

Explanation:

Which of the following statements about the ice ages is true? a. An ice age will never come again. b. The causes of ice ages are well known. c. During the ice ages, icy glaciers covered much of the continents. d. There were no living organisms during the ice ages.

Answers

Answer:

C

Explanation:

its a fact and in Biology we take facts over expectations

100pts!!! PLEASE HELP quickly!!
1. For today’s weather, it’s up to you to decide where the fronts are located. Draw the fronts on the map. Explain your reasoning.

Answers

As per the weather map of north America the regions of high and low pressure are given along with the cloudiness and range of temperatures

The warm and fold fonts are affected by the cloud covers and hence affect the temperature of the region. The cold front will be along the borer of 40 and 50°. The northeastern region shows maximum cloud cover and a low pressure. As compared to the western and southern region have have high temperatures and experienced high pressure. The winds will below from the high pressure to low pressure and hence create instability cover the north eastern parts.

Hence the fronts are located north east and central zone.

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Which of the following is NOT an ecosystem
service that forests provide?
habitat for wildlife
reduce soil erosion
lumber
carbon sink
all of the choices are ecosystem services

Answers

Answer:

All of the choices are ecosystem services.

Explanation:

Trees' roots hold soil down so it doesn't move everywhere and they recycle carbon into oxygen. In addition, they provide us wood and beautiful wildlife!

Have a great day!

The ecosystem services are all the benefits provided by the ecosystem to human. Otion A) habitat for wildlife is not an ecosystem service.

What are the Ecosystem Services?

When talking about ecosystem services, we are referring to the goods and services offered by ecosystems to human populations

There are different types of ecosystemic services:

Provision or supply:

These are the products obtained by nature to be used or consumed, directly or with previous processing.

Among them, we can mention food, clear fresh-water, fertile soils, geotic materials, raw materials (used for clothing, construction), renewable fuels, biochemical compounds, pharmacological/medicinal resources, and others.

Regulation:

Refers to ecological processes that improve life.

Among others, we might mention climate regulation, CO₂ absorption, water purification, air purification, erosion control, natural disaster avoidance such as flooding, soil formation and fertility maintenance, nutrient cycling, waste recycling, pests/plagues control, etc.

Cultural:

Refers to the benefits that are not material.

Ecosystems also provide a recreational place or area to spend time, learn. They are a spiritual/religious space, a source of inspiration. They are considered to be cultural patrimony and the source of scientific knowledge.

Among th options, the one that is not a ecosystemic service is option A) habitat for

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.

How humans use Nitrogen and phosphorus to make more food?
A. Dog foods
B. Fuels
C. Fertilizers
D. Cars

Answers

Answer:

C. Fertilizers  

Explanation:

Put these in order from least to greatest amounts of energy made.
= Aerobic respiration
= Fermentation
= Glycolysis

Answers

Answer:

respiration makes the most (38 ATP) and the other 2 are if not the same at least very similar both release 2 ATP 2 NADH and 2 pyruvate

Explanation:

Large multicellular organisms are made of a wide variety of cell types. Do
all of the types of cells pass through the cell cycle at the same rate? *
1 point
Yes. All of the cells divide at approximately the same times throughout the life of the
organism.
Yes. All of the cells divide at approximately the same rate, although they may divide at
different times.
No. Some specialized cells, such as skin cells, divide much more rapidly than other
specialized cells
No. Some specialized cells, such as skin cells, divide much more slowly than other
specialized cells.

Answers

Answer:

Yes, All of the cells divide at approximately the same rate, although they may divide at different times

Those organisms which are made up of more than one cell are called multicellular organisms.

These are a few examples of multicellular organisms:-

PlantsAnimalsFungi

Multicellularity helps them to perform various work at the same time. To maintain the same number of cells in an organism, its body starts cell division.

It is not necessary for the host to divide all the cells at the same time.

Hence the correct option is Yes. All of the cells divide at approximately the same rate, although they may divide at  different times.

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A variety of opium poppy (Papaver somniferum L.) having lacerated leaves was crossed with a variety that has normal leaves. All the F1 had lacerated leaves. Two F1 plants were interbred to produce the F2. Of the F2, 249 had lacerated leaves and 16 had normal leaves. Give genotypes for all the plants in the F1, and F2 generations. Explain how lacerate leaves are determined in the opium poppy. (Section 5.2)

Answers

Answer:

The correct answer is-

F1 -  AaBb (lacerate)

F2 - A_B_; A_bb; and aaB_ (lacerate)

     - aabb (normal)

2. Two genes, with a dominant allele at either or both loci.

Explanation:

The given information gives THE following data:

Dominant: Lancerate leaves - AABB

Recessive: normal leaves - aabb

F1 has - all Lacerated leaves - AaBb

F2 by selfing F1:

         AB               Ab         aB         ab

AB    AABB        AABb      AaBB    AaBb

Ab     AABb       AAbb      AaBb     Aabb

aB     AaBB       AaBb       aaBB     aaBb

ab     AaBb       Aabb       aaBb      aabb

Here, 15/16 = lacerate which is 0.94 which is equal to the value of lacerate given in the question - 249/265 = 0.94

And normal 1/16 = 0.062 is almost same as 16/265 = 0.060

Thus, the genotypes of -

F1 -  AaBb (lacerate)

F2 - A_B_; A_bb; and aaB_ (lacerate)

     - aabb (normal)

Explain how to revise the following DNA model to form mRNA


AACCTGGGACTATGAT

Answers

Uuggacccugauacua is the answer

what do you call the reproduction in plants where the male and female parts of the flowers of the plants are involved?
A.asexual
B.budding
C.pollination
D.sexual​

Answers

Answer:

your answer would be d. sexual

Please what's an ecosystem​

Answers

An ecosystem is a geographic area where plants, animals, and other organisms, as well as weather and landscape, work together to form a bubble of life. Ecosystems contain biotic or living, parts, as well as abiotic factors, or nonliving parts.

ECOSYSTEM:

Ecosystem is the complex of living organisms, their physical environment, and all their interrelationships in a particular unit of space.

A donkey and a horse can be mated to produce a mule, but mules are sterile and cannot have
offspring. Infer whether donkeys and horses should be considered the same species. Explain
your answer using textual evidence.

Answers

Answer:

But hinnies and mules can't have babies of their own. They are sterile because they can't make sperm or eggs. They have trouble making sperm or eggs because their chromosomes don't match up well. ... A mule gets 32 horse chromosomes from mom and 31 donkey chromosomes from dad for a total of 63 chromosomes

Answer:

But hinnies and mules can't have babies of their own. They are sterile because they can't make sperm or eggs. They have trouble making sperm or eggs because their chromosomes don't match up well. ... A mule gets 32 horse chromosomes from mom and 31 donkey chromosomes from dad for a total of 63 chromosomes.

Explanation:

7. Explain how the equations for photosynthesis and cellular respiration compare.

Answers

Answer: In Photosynthesis, carbon dioxide and water is yielded to glucose and oxygen. In respiration, glucose and oxygen is yielded to carbon dioxide and water. C6H12O6 (glucose) + O2(oxygen) → CO2(Carbon Dioxide) + H2O(water) + ATP energy. The products of one process are the reactants of the other. Notice that the equation for cellular respiration is the direct opposite of photosynthesis: Cellular Respiration: C6H12O6 + 6O2 → 6CO2 + 6H2O. Photosynthesis: 6CO2 + 6H2O → C6H12O6+ 6O.

Explanation:

PLEEASEEEEEEEEE HEELPPPPPPPPPPPP

Answers

1) The new blood cells are created in the in the bone marrow , located inside the bone .
2) stores fat
3)calcium
4) tough tissue

Answer:

1) bone marrow

2)stores fat

3) calcium

4)tough tissue

77 POINTS, PLEASE HELP ASAP

1): Lily is dressing up as a chicken for Halloween this year and is flapping her arms like a bird as she walks from house to house. As Lily flaps her arms down to her sides, what type of movement is occurring?

2): Katie loves pretending that she’s a human cannonball. As she jumps off the diving board, she assumes the proper position before she pounds into the water: head and thighs tucked against her chest; back rounded; arms pressed against her sides while her forearms, crossed in front of her shins, hold her legs tightly folded against her chest. What movement term would best describe the positioning of Katie’s vertebral column, head, thighs, lower legs and lower arms? HINT: She is about as far from the anatomical position as she can get.

Answers

Answer:

1. abduction & abduction

2. flexed

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