Pancytopenia is common in SLE, and is caused by what?

The funding agency which focuses most on outcomes research is the Agency for Healthcare Research and Quality (AHRQ).

AHRQ is a federal agency that conducts research to improve the quality, safety, efficiency, and effectiveness of healthcare services. Outcomes research, also known as patient-centered outcomes research (PCOR), aims to measure and evaluate the impact of healthcare interventions on patient outcomes, such as health outcomes, quality of life, and patient satisfaction.

AHRQ's mission includes supporting research that generates evidence on the effectiveness and safety of healthcare interventions, as well as promoting the translation of research findings into practice to improve patient outcomes. As such, AHRQ is often considered a leading funding agency for outcomes research in the United States.

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--The given question is incomplete, the complete question is

"The funding agency that focuses most on outcomes research is --------."--

Combined oral contraceptives (COCs) are a type of birth control that contains a combination of estrogen and progestin.

Monophasic COCs have a fixed dose of hormones throughout the cycle, unlike multiphasic COCs, which have varying doses of hormones.

The standard starting dose of ethinyl estradiol in a monophasic COC regimen is typically 20-35 micrograms (mcg) per day.

This dose is usually contained in a single pill that is taken once a day at the same time each day.

The appropriate starting dose of ethinyl estradiol may depend on various factors, including the patient's medical history, age, and any other medications they may be taking.

It's important to consult with a healthcare provider to determine the appropriate dose and regimen for each patient.

When starting a monophasic COC regimen, the patient should be advised to take the first pill on the first day of their menstrual cycle or on the first Sunday after the start of their menstrual cycle.

They should take one pill every day, at the same time each day, without skipping any pills.

It's important to note that COCs containing ethinyl estradiol carry certain risks and potential side effects, and they are not suitable for everyone.

Patients should be fully informed of the risks and benefits of this type of contraception and should be monitored regularly by a healthcare provider while taking it.

Regular check-ups with a healthcare provider are important to ensure that the COC is working effectively and to monitor for any potential adverse effects.

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Compared to spontaneous ventilation, the Vd/Vt ratio (dead space ventilation to tidal volume ratio) when a patient is placed on a mechanical ventilator usually increases.

Spontaneous ventilation refers to the process of breathing in which the patient is able to inhale and exhale on their own without the assistance of mechanical ventilation. This is in contrast to assisted ventilation, where a machine provides breaths to the patient, or controlled ventilation, where the patient's breathing is completely controlled by the ventilator.

The increase occurs due to the additional dead space created by the ventilator tubing and the potential for overdistension of the alveoli, which can lead to less efficient gas exchange. Mechanical ventilation can also help to maintain appropriate tidal volumes, which can be important for avoiding lung injury and maintaining gas exchange.

In general, the goal of mechanical ventilation is to optimize oxygenation and carbon dioxide elimination while minimizing the risk of lung injury.

Therefore the answer is "increases".

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The ratio of compressions to ventilations for two-rescuer CPR on an infant or child is 15 compressions to 2 ventilations. It's important to maintain a steady rhythm during CPR and alternate roles between the rescuers every 2 minutes to prevent fatigue. It's also crucial to make sure that compressions are being done effectively and that the ventilation technique is appropriate for the age of the victim.

To perform two-rescuer CPR on an infant or child, follow these steps:
1. One rescuer begins chest compressions: Place the heel of one hand (for a child) or two fingers (for an infant) in the center of the chest and perform 15 compressions at a rate of 100-120 compressions per minute.
2. The second rescuer provides ventilations: After the first rescuer completes 15 compressions, the second rescuer gives 2 breaths using a bag-valve-mask (BVM) or mouth-to-mask device, ensuring the breaths are delivered over 1 second and cause visible chest rise.
3. Continue this cycle: The rescuers continue the 15:2 ratio of compressions to ventilations without interruption until emergency help arrives or the patient shows signs of life.

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Hereditary angioedema is caused by a deficiency in the C1 esterase inhibitor (C1-INH), which is a protein involved in the regulation of the complement and kinin systems.

ACE inhibitors are contraindicated in patients with hereditary angioedema because they can increase bradykinin levels, which can exacerbate angioedema symptoms. Excess bradykinin can trigger recurrent episodes of angioedema, which can be life-threatening if it affects the airway.

Therefore, alternative medications that do not affect the kinin system, such as angiotensin receptor blockers (ARBs), are preferred for patients with hereditary angioedema who require antihypertensive therapy.

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The question is -

What is the deficiency responsible for hereditary angioedema, and why are ACE inhibitors contraindicated in patients with this condition?

During the normal movement of the mandible in a protrusile contact, the front part of the upper jawbone (central maxilla) comes into contact with the mandible.

When the mandible moves forward in a protrusile movement, several key factors come into play:

In addition to these factors, there are other factors that can affect the normal movement of the mandible, including tooth wear, misalignment of the teeth, and temporomandibular joint (TMJ) disorders.

If you experience pain or discomfort when moving your jaw, or if you notice that your teeth are not coming together properly, it is important to see a dentist or a doctor for evaluation and treatment.

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The maximal reduction in the cerebral metabolic requirement for oxygen (CMR[tex]O_{2}[/tex]) achievable exclusively through the use of high-dose propofol is approximately 50%.

Propofol is a sedative-hypnotic agent that acts on the GABA-A receptors in the brain, leading to an overall decrease in cerebral metabolism. High-dose propofol administration has been shown to cause a dose-dependent decrease in CMR[tex]O_{2}[/tex], with a maximal reduction of approximately 50%.

However, it is important to note that the reduction in CMR[tex]O_{2}[/tex] achieved with high-dose propofol may not necessarily correspond to a proportional reduction in cerebral blood flow (CBF). The relationship between CMR[tex]O_{2}[/tex] and CBF is complex and depends on various factors, including cerebral autoregulation and the underlying disease process.

Therefore, the use of high-dose propofol to reduce CMR[tex]O_{2}[/tex] should be carefully considered in the context of the patient's clinical situation and monitored closely to ensure adequate cerebral perfusion.

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Placing the stock with the earliest expiration date at the front of the product supply is good because it promotes proper stock rotation and reduces product waste. This ensures that items are sold and used before they expire, maintaining the quality and safety of the products.

Yes, placing the stock with the earliest expiration date at the front of the product supply is a good practice. This ensures that the products are used before they expire, reducing waste and ensuring that customers receive fresh and high-quality products. Additionally, it helps in managing inventory and reducing losses due to expired products.

The stock with the earliest expiration date should be placed in the front of the product supply to encourage proper stock rotation and minimise product waste. Thus, the products' quality and safety are maintained and they are sold and consumed before they go bad.

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Symmetric stretches do not show up in IR (infrared) spectra due to their inability to induce a change in the dipole moment of the molecule.

Infrared spectroscopy measures the vibrations of molecular bonds, and the absorption of IR radiation occurs when the frequency of the radiation matches the frequency of molecular vibration. This process is called the selection rule, and it is crucial for the appearance of vibrational bands in an IR spectrum.

For a vibration to be IR-active, there must be a change in the dipole moment of the molecule during the vibration. In symmetric stretches, the overall molecular geometry remains unchanged during the stretching process, and there is no change in the distribution of charges. As a result, the dipole moment remains constant, and the symmetric stretching vibration does not interact with the infrared radiation.

In summary, symmetric stretches do not show up in IR spectra because they do not cause a change in the dipole moment of the molecule, preventing the interaction with the infrared radiation and the subsequent absorption of energy.

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Chloroprocaine is the drug least likely to undergo fetal ion trapping.

Fetal ion trapping occurs when a drug crosses the placenta and becomes ionized in the more acidic fetal environment. The ionized form of the drug is less lipophilic and has difficulty crossing back into the maternal circulation, resulting in a higher concentration of the drug in the fetus.

Considering the properties of the mentioned drugs:
1. Lidocaine: Has a pKa of 7.9 and a higher likelihood of undergoing fetal ion trapping.
2. Chloroprocaine: has a pKa of 8.7 and undergoes rapid hydrolysis in the plasma, making it the least likely to undergo fetal ion trapping.
3. Mepivacaine: It has a pKa of 7.6, which makes it more likely to undergo fetal ion trapping.
4. Bupivacaine: It has a pKa of 8.1, which also makes it more likely to undergo fetal ion trapping.

Based on the information provided, (b) chloroprocaine is the drug least likely to undergo fetal ion trapping.

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Pericarditis isn't always treated with NSAIDs. If BUN (blood urea nitrogen) levels are high, it may indicate kidney issues, and the treatment should be adjusted accordingly. In such cases, alternative treatments such as colchicine or corticosteroids may be used.

If a patient with pericarditis has a high blood urea nitrogen (BUN) level, it may indicate impaired kidney function. In this case, treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) may not be appropriate as they can further harm the kidneys. Instead, the doctor may prescribe alternative medications such as colchicine or corticosteroids to manage the inflammation and pain associated with pericarditis. It is important to follow the treatment plan recommended by your doctor and monitor your kidney function closely during treatment.

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A humeral neck fracture with malunion may result in an altered end feel for passive range of motion (PROM) accessory movements. In a normal joint, the end feel is the resistance experienced when a joint is passively moved to its limit. There are three primary types of end feels: bony, soft tissue approximation, and tissue stretch.

In the case of a humeral neck fracture with malunion, the expected end feel for PROM accessory movements would likely be different from a normal joint, as the malunion may lead to structural changes and limited mobility. The end feels could potentially be bony, due to the altered bone structure and abnormal bone contact. Additionally, soft tissue approximation or tissue stretch end feels might also be present if there is excessive scar tissue or muscle tightness, which could further limit joint mobility.

Overall, the end feels for PROM accessory movements following a humeral neck fracture with malunion can vary depending on the specific changes to bone structure and surrounding soft tissue.  clinicians need  to assess each case individually to determine the appropriate course of treatment and rehabilitation.

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The purpose for routinely screening diabetes mellitus patients for microalbuminuria is to monitor the development of diabetic nephropathy.

Diabetic nephropathy is a common complication of diabetes that affects the kidneys, leading to progressive kidney damage and eventually kidney failure. Microalbuminuria is an early sign of diabetic nephropathy, which is why it is recommended that patients with diabetes undergo routine screening for microalbuminuria.

Monitoring microalbuminuria levels can help identify patients who are at increased risk of developing diabetic nephropathy and allow for early intervention and management to slow or prevent progression of kidney disease.

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Nurses play a crucial role in caring for children, both in hospital settings and in the community. They provide direct care by promoting health and preventing illness through health promotion and health maintenance activities.

They also provide nursing care for children with various health conditions, such as chronic illnesses, acute injuries, and infectious diseases. This includes administering medications, monitoring vital signs, and performing procedures such as wound care and blood draws.

In addition to providing direct care, nurses educate patients and families on topics such as medication management, nutrition, and disease prevention. They also act as advocates for their patients, ensuring that they receive appropriate care and treatment. Nurses also serve as case managers, coordinating care and working with interdisciplinary teams to provide comprehensive care for children.

Perhaps most importantly, nurses help minimize the psychological and physical distress experienced by children and their families. They provide emotional support and comfort to patients and families during challenging times and work to create a healing environment that supports the well-being of all involved. Overall, the role of nurses in caring for children is multifaceted and critical to ensuring positive health outcomes for this vulnerable population.

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The best response by the nurse would be to explain that migraine headaches can differ between individuals, regardless of gender.

There are certain differences in the prevalence and presentation of migraine headaches between men and women, but severity and duration of migraine headaches can vary within the same gender as well. The nurse can explain that various factors can contribute to the severity and duration of migraine headaches, including genetics, lifestyle factors, stress, and hormonal fluctuations.

Additionally, migraine headaches can be triggered by different things for different people, such as certain foods, environmental factors, or physical activities. The nurse can also encourage the client to keep a headache diary to track their symptoms, triggers, and patterns. This can help the client and their healthcare provider develop an individualized treatment plan to manage their migraines.

It's important to recognize that migraines are a complex and individualized condition that can vary from person to person, and there is no one-size-fits-all answer to why they might be more severe or longer in duration for one person compared to another.

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The another name for "enrolled" in clinical trial may also be referred to as "enlisted," "registered," or "enrolled subjects" .

"Enrolled" is a common term used in clinical trials to refer to participants who have been officially registered or recruited into a clinical trial and have met the eligibility criteria for participation.

Other synonyms which are sometimes used interchangeably with "enrolled" include "randomized," "assigned," or "included" when referring to participants who have been allocated to a specific study arm or group within the trial.

These terms are commonly used in the context of clinical research to describe the status of participants who have formally joined a clinical trial and are actively participating in the study.

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The disease that presents with lower back pain, relieved with exercise, and worse in the morning is likely to be ankylosing spondylitis. The diagnosis is made with a combination of physical examination, imaging studies, and laboratory tests.

Ankylosing spondylitis is a type of inflammatory arthritis that primarily affects the spine and sacroiliac joints. It commonly presents with lower back pain that is worse in the morning and relieved with exercise. Imaging studies such as X-ray, MRI, and CT scan can reveal characteristic changes in the spine and sacroiliac joints, including fusion of the vertebrae and inflammation of the joints. Laboratory tests may also be useful in the diagnosis, including the HLA-B27 genetic marker and blood tests for inflammation markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR).

In summary, ankylosing spondylitis should be suspected in a 20-year-old patient with lower back pain that is relieved with exercise and worse in the morning. The diagnosis is made through a combination of physical examination, imaging studies, and laboratory tests.

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The most appropriate nursing intervention for a client with chronic anxiety disorder reporting chest pain is to assess the client's vital signs and provide reassurance.

Anxiety can cause chest pain, and it is important to rule out any other potential causes of chest pain. Taking the client's vital signs can help to identify any underlying physical conditions that may be causing the chest pain.

Additionally, providing reassurance to the client can help to reduce their anxiety and help them to relax. It is important to provide the client with a safe and supportive environment to help them to cope with their anxiety and chest pain.

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The client's measured weight and BMI two years following weight reduction is an example of a long-term outcome, option (c) is correct.

A long-term outcome refers to the results of an intervention or treatment that are observed over a considerable period, usually several years after the intervention. In this scenario, the client and care provider has identified that a 30-pound weight loss is needed to achieve the desired BMI.

Two years following the weight reduction, the measured weight and BMI can be considered a long-term outcome. This is because the outcome is being observed over a considerable period after the intervention (two years), which allows for a more accurate assessment of the sustainability of the weight loss, option (c) is correct.

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The correct question is:

A client and care provider have identified that a 30-pound weight loss is needed to attain the desired Body Mass Index (BMI). The client's measured weight and BMI two years following weight reduction is an example of

a. a performance-related outcome.

b. an intermediate outcome.

c. a long-term outcome.

d. a short-term outcome.

The recommended depth of compression for an infant is approximately one-third the depth of their chest, which is around 1.5 inches or 4 cm.

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The priority of care for a 12-year-old child with sickle cell anemia who is admitted during a vasoocclusive crisis is Pain management.

Option (a) is correct.

Pain is a common symptom experienced by individuals with sickle cell anemia during a vasoocclusive crisis, which occurs when sickled red blood cells block blood vessels, causing tissue damage and ischemia. Effective pain management is essential to provide relief to the child and improve their overall well-being.

Pain management may involve administering analgesics, such as opioids or nonsteroidal anti-inflammatory drugs (NSAIDs), and using nonpharmacological interventions, such as distraction techniques or relaxation exercises. The goal of pain management is to achieve adequate pain relief while minimizing the risk of side effects associated with pain medications.

Therefore, the correct option is (a) Pain management

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The question is incomplete. the complete question is:

a 12-year-old child with sickle cell anemia is admitted during a vasoocclusive crisis. which is the priority of care for this child?

a. Pain management

b. Oxygenation support

c. Fluid and electrolyte balance

d. Infection prevention

If the FDA or pharmaceutical manufacturer recalls a product, the technician should immediately stop dispensing or using the product and follow the guidelines provided by the recall notice.

The situation may include removing the product from inventory, notifying patients or customers who may have received the product, and returning the product to the manufacturer or distributor as directed. It is important for technicians to take recall notices seriously and to act quickly to prevent harm to patients or customers. The pharmacy should work with the manufacturer and the FDA to ensure that the recalled product is properly disposed of or returned to the manufacturer. The pharmacy should also take steps to prevent the recalled product from being dispensed again.

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A lesion in the anterior communicating artery, which is a branch of the internal carotid artery, can cause compression or damage to the optic chiasm and result in bitemporal hemianopia.

a lesion in the anterior communicating artery can cause compression or damage to the optic chiasm, which is a crossing point of the optic nerves, resulting in bitemporal hemianopia. The anterior communicating artery connects the two anterior cerebral arteries and supplies blood to the medial portion of the frontal lobes and the anterior portion of the corpus callosum.

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Complete Question

A lesion in which artery can cause bitemporal hemianopia?

The most important question that the nursing student should ask the patient about personal hygiene is: "May I help you with a bed bath now or later this morning?"

This allows the patient to have a say in their own care and ensures that the nursing student is providing appropriate care tailored to the patient's preferences. The statement allows the patient to show control over his care and hygiene. It respects the dignity of the patient. Option A is a close-ended question that only leaves the patient with two options and limits his response. Option C is authoritative of the nursing student which will not be appreciated by many individuals. Option D is completely irrelevant to the patient's condition, rather it talks about the student's lifestyle.

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If a patient is suspected of having an ectopic pregnancy and has a quantitative beta HCG level less than 6500, further evaluation is required.

Ectopic pregnancy occurs when the fertilized egg implants outside of the uterus, usually in the fallopian tube. The first step in evaluation is to perform an ultrasound to confirm the location of the pregnancy. If the ultrasound shows an empty uterus and no evidence of a pregnancy in the fallopian tubes, then the possibility of an ectopic pregnancy is high.

In this case, the patient should be treated with methotrexate, a medication that stops the growth of the pregnancy and allows the body to reabsorb it. However, if the ultrasound shows evidence of a pregnancy in the uterus or the fallopian tubes, then further monitoring is required.

The patient should be closely monitored for signs of a ruptured ectopic pregnancy, such as abdominal pain, vaginal bleeding, or lightheadedness. If the patient develops any of these symptoms, immediate medical attention is necessary. In summary, if a patient is suspected of having an ectopic pregnancy and has a quantitative beta HCG level less than 6500, an ultrasound should be performed to confirm the location of the pregnancy.

If the pregnancy is located outside of the uterus, then treatment with methotrexate is recommended. If the pregnancy is located in the uterus or the fallopian tubes, the patient should be closely monitored for signs of a ruptured ectopic pregnancy.

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The lupus antibody that is most strongly associated with kidney disease is anti-double stranded DNA (anti-dsDNA) antibody.

In patients with lupus, the presence of anti-dsDNA antibodies has been shown to correlate with the development of lupus nephritis, which is a type of kidney inflammation that is a common complication of systemic lupus erythematosus (SLE). Anti-dsDNA antibodies are also useful for monitoring disease activity and response to treatment in patients with lupus nephritis. However, it's important to note that not all patients with lupus nephritis have detectable levels of anti-dsDNA antibodies, and not all patients with anti-dsDNA antibodies develop lupus nephritis.

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In the intercuspal position, the lingual cusp of a mandibular first premolar usually occludes with the mesial marginal ridge of the maxillary second premolar and the distal marginal ridge of the first premolar. This option is represented by choice 1.

To explain further, the intercuspal position refers to the position where the upper and lower teeth fit together when the jaws are closed, providing maximum contact between the opposing teeth. The lingual cusp of a mandibular first premolar refers to the innermost elevated point on the chewing surface of the lower first premolar tooth.
In this position, the lingual cusp of the mandibular first premolar interacts with the marginal ridges of the adjacent maxillary teeth. The mesial marginal ridge of the maxillary second premolar is the elevated border on the front part of the chewing surface of the upper second premolar tooth, while the distal marginal ridge of the first premolar is the elevated border on the back part of the chewing surface of the upper first premolar tooth.
In conclusion, when the jaws are in the intercuspal position, the lingual cusp of the mandibular first premolar occludes with the mesial marginal ridge of the maxillary second premolar and the distal marginal ridge of the first premolar, as stated in option 1.

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The appropriate action by the nurse when auscultating an arteriovenous (AV) fistula and noting a bruit is to document the presence of the bruit, option 1 is correct.

A bruit is a sound that can be heard when there is turbulent blood flow through an artery or vein. In the case of an arteriovenous (AV) fistula, a bruit is a normal finding and indicates that blood is flowing properly through the fistula.

It is not necessary to contact the healthcare provider or assess for signs and symptoms of infection or fluid overload in response to hearing a bruit in an AV fistula. Documentation of the presence of the bruit is important for ongoing assessment and evaluation of the fistula's function, option 1 is correct.

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The correct question is:

When auscultating an arteriovenous (AV) fistula, a bruit is noted. What is the appropriate action by the nurse?

1. Document the presence of a bruit.

2. Contact the healthcare provider.

3. Assess for signs and symptoms of infection.

4. Assess for signs and symptoms of fluid overload.

A gastric ulcer located on the lesser curvature of the stomach can erode into the left gastric artery.

A gastric ulcer found on the lesser curvature of the stomach can erode into the left gastric artery. This can cause bleeding and potentially life-threatening complications. It is important to seek medical attention if you suspect you have a gastric ulcer.

Peptic ulcers are open sores that develop on the inside lining of your stomach and the upper portion of your small intestine. The most common symptom of a peptic ulcer is stomach pain.

Gastric ulcer treatment depends upon the cause. Treatment for ulcers generally involves eliminating factors that interrupt the healing

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Epic calculates the Ideal Weight by first determining a healthy BMI range, and then using the individual's height to find the corresponding weight range.

Epic calculates the Ideal Weight using the body mass index (BMI) formula, which takes into account a person's height and weight. The formula is as follows:

BMI = weight (in kilograms) / height^2 (in meters)

Step 1: Epic uses the Body Mass Index (BMI) as a basis for calculating the Ideal Weight. BMI is calculated using an individual's height and weight, with the following formula: BMI = weight(kg) / height(m)^2.

Step 2: Epic determines a healthy BMI range, typically between 18.5 and 24.9, as this range is associated with a lower risk of health issues.

Step 3: Using the healthy BMI range and an individual's height, Epic calculates the Ideal Weight range by rearranging the BMI formula: Ideal Weight = healthy BMI * height(m)^2.

Step 4: Epic provides an Ideal Weight range in kilograms, which represents the range of weights that correspond to the healthy BMI values for the individual's height.

In summary, Epic calculates the Ideal Weight by first determining a healthy BMI range, and then using the individual's height to find the corresponding weight range.

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