Describe the typical principles used to identify topogenic sequences within proteins and how these principles can be used to develop computer algorithms. How does the identification of topogenic sequences lead to prediction of the membrane arrangement of a multipass protein

Answers

Answer 1

Answer:

Topogenic sequences share a series of structural features, and thereby computational algorithms can be used to predict these protein-membrane segments  

Explanation:

Topogenic sequences are protein segments formed by alpha-helical transmembrane domains, which are required for the insertion of membrane proteins. These domains share a series of well-defined features: they are composed of segments of about 20 hydrophobic amino-acid residues. In consequence, computational algorithms can be designed to identify protein patterns that fulfill these structural requirements (i.e. segments with a length of 20 residues, hydrophobic level, etc). The models assign a similarity threshold (threshold value) that predict if the similarity level of the protein pattern is good enough to detect a topogenic segment.


Related Questions

mention two morphological differences between pteridophyte
and spermatophyte​

Answers

Answer:

The main difference between these two classes is that: Pteridophytes are vascular plants but they do not produce flowers and seeds which mean their source of reproduction is unknown or hidden. Examples are ferns, horsetails and lycophytes. On the contrary, Spermatophytes as the name indicates, are seed bearing plants.

Explanation:

Answer:

THE DIFFERENCE is that spermatophyte is (botany) any plant that bears seeds rather than spores while pteridophyte is any plant of the division pteridophyta, of simple vascular plants that reproduce via spores rather than seeds and that alternate generations of diploid (sporophyte) and haploid (gametophyte or prothallus) forms

Explanation:

Plants combine carbon dioxide and water to make what
substance?
O A. Glucose
O B. Ammonia
O C. Peptide
O D. Nitrogen
SUBMIT

Answers

Answer:

A. glucose right good brilliant

A 45 year old man had coronary artery stents placed 2 days ago. Today, he is in severe distress and reporting crushing chest discomfort.

Answers

Answer:

idk man

Explanation:

What happens to grasslands and wetlands as forests are used up?

Answers

Answer:

they dry

Explanation:

because forests are sources of rain and without rain wetlands can't have water and grass can't grow n grassland

Answer:

they become really dry good luck men

what is 9 + 10??? VERY IMPORTANT

Answers

Answer:

9 + 10 = 19

the answer is = 19

A variety of factors influence enzyme activity. Substances that bind to the enzyme and interfere with substrate binding or catalysis are inhibitors. Identify the type of inhibition associated with each of the descriptions and examples by classifying each statement as irreversible, competitive, or mixed inhibition.

Answers

Answer:

Explanation:

Irreversible inhibitors are inhibitors whose action are not reversible. They function by modifying enzyme in a covalent way leading to the formation of new functional group.

Irreversible inhibitors are specific to certain enzymes. Examples is inhibitor that are suicidal they makes inhibitor reactive.

Competitive inhibition are Inhibitor that are competitive in nature they resemble one of the substrate of the enzyme and are been bind to by mistake. Example is an inhibitor that resemble folate an enzyme substrate. Enzyme therefore binds to the inhibitor assuming its folate because they are identical.

H
Br
H
Br
H
Br
Br
H
What best describes these two molecules?
They are not isomers.
They are structural isomers.
They are geometric isomers.
They are both structural and geometric isomers.

Answers

Answer:

It's C

Explanation:

They are geometric isomers. Thus option C is the correct answer.

what is isomers ?

Two chemical species with the same number and types of atoms but different configuration are called as isomers, the spontaneous process by which isomers are formed called isomerization.

This process is independent of bond energy of the configurations.

Different types of isomers are structural isomers, geometric isomers, stereoisomers, optical isomers.

The major type called structural Isomers where atoms and functional groups are differently joined with each other. For example, 1-fluoropropane and 2-fluoropropane positional change.

Another types is stereoisomers formed between atoms and functional groups with differential geometrical positioning.

This class include enantiomers which are non-superimposable mirror images of each other and have chiral centers. example are D-threose and D-erythrose.

In stereoisomers, the class of diastereomers have different physical properties and reactivities.

Thus option C is the correct answer.

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5. Find the LC.M of XX,X-1,X-X​

Answers

Answer:

-1 I believe

Explanation:

Which molecular formula corresponds to this model of a chemical compound? (black = carbon; red = oxygen; white =hydrogen)

Cz(OH)4
C2H204
C₂H4O2
C4H₂O2

Answers

C2H204 is the formula

HHH
НОН
HHH
но-н
нЩн
нон
HHH
HHH
HHH
List the number of each atom in the formulas above:
Н
О
0

Answers

Answer:

According to the diagram above, there are 8 Hydrogen, 1 Oxygen and 3 Carbon .

Answer:

3 carbons

Explanation:

Mendel used monohybrid crosses to study the inheritance of pea plant characteristics. In one of his classic experiments, Mendel crossed a purple-flowered plant with a white-flowered plant. All of the offspring plants produced purple flowers.
1. Using the symbols P for the purple allele and p for the white allele, provide the following information:
A. What the genotypes of the Parental Generation plants?
Purple parent: White parent:
B. What is the genotype of the F1 generation?
C. Organisms with two copies of the same allele are called
D. Organisms with two different alleles are called
2. When is it necessary to perform a test cross?
3. In rabbits, brown coat (B) is dominant to white coat (b). A rabbit breeder wants to know the genotype of his best looking male brown rabbit using a test cross. He has brown females and white females available to conduct his breeding experiments.
A. What should be the coat color of the female he must use in this test cross?
B. If the test cross produces seven (7) brown rabbits and one (1) white rabbit, what is the genotype of the brown male rabbit?
4. How is Mendel's Law of Independent related to the events of Meiosis?
5. In your own words, state the Law of Segregation
There are other patterns of inheritance that require explanations beyond the predictions of Mendel's Law of Dominance and Segregation. These patterns are known in biology as non-Mendelian inheritance and include:______.
A. Incomplete dominance
B. Codominance
C. Multiple Alleles
D. Pleiotropy (explained in the first assigned video)
E. X-linked inheritance
F. Epistasis
6. Write in the space provided the type of non-Mendelian inheritance from the list above that matches the descriptions or the examples listed below:
1. When a gene has more than two allele variants.(Example)
2. When a single gene or allele controls the expression of 2 or more traits.
3. When offspring show a blended phenotype, a physical appearance intermediate to the phenotype of both parents
4. When an allele is carried in the X chromosome.

Answers

Answer:

Explanation:

A. To produce all purple flowers from a cross between purple and white flowers, it means the parents genotype are dominant homozygous purple and the recessive homozygous white ( PP and pp)

B. The F1 generation will possess a phenotype of purple colour with genotype ( Pp )- heterozygous

C. Organisms with two copies of the same allele are called homozygotes

D. Organisms with two different alleles are called heterozygotes

2. When is it necessary to perform a test cross?

This test is only perform when the identity/genotype of one of the parents is unknown then a testcross is carried out.

3.A The coat color of the female he must use is white...a testcross is done with the recessive parents

B. The genotype of the male brown rabbit is Bb to produce a white rabbit.

4. The law of independent assortment amd meiosis relates in that the independent assortment law talks about independent separatíon of gens from each other and in meiosis, it takes into account the independent separation of homologous chromosomes.

5. The law of segregation of genes takes into account that an individual that is diploid possessing 2 copies of a gene/alleles on each homologous chromosome, that each of these alleles segregation or separate into each gametes, as one allele per gamete.

5. Non-Mendelian inheritance includes all listed below

6.

1. When a gene has more than two allele variants - multiple alleles

2. When a single gene or allele controls the expression of 2 or more traits - Pleitropy e.g. as in the ABO blood group

3. When offspring show a blended phenotype, a physical appearance intermediate to the phenotype of both parents: incomplete dominance

4. When an allele is carried in the X chromosome - X linked inheritance

Answer: the biological

Explanation: the biological


The following are examples of characteristics that can be inherited except
(a)intelligence (b) complexion (C) type of blood (d) shape of head (e) sex of the child​

Answers

Answer:

sex of the child

Explanation:

Are tanning beds safe?

Answers

Answer:

Tanning beds are NOT safer than the sun.

Explanation:

Science tells us that there's no such thing as a safe tanning bed, tanning booth, or sun lamp. Just one indoor tanning session can increase the risk of developing skin cancer (melanoma by 20%, squamous cell carcinoma by 67%, and basal cell carcinoma by 29%).

The trait for medium-sized leaves in iris is determined by the genetic condition PP'. Plants with large leaves are PP, whereas plants with small leaves are P'P'. The trait for red flowers is controlled by the genes RR, pink by RR', and white by R'R'. A cross is made between two plants each with medium-sized leaves and pink flowers. If they produce 640 seedlings, what would be the expected phenotypes, and in what numbers would they be expected

Answers

Answer:

See the answer below

Explanation:

Medium size leaves genotype = PP'

Large leaves genotype = PP

Small leaves genotype = P'P'

Red flower genotype = RR

Pink flower genotype = RR'

White flower genotype = R'R'

Two plants each with medium-sized leaves (PP') and pink flowers (RR') were crossed.

PP'RR'   x   PP'RR' (let PP' = Aa and RR' = Bb)

Progeny and expected phenotypes

1 PPRR - large leaves, red flower = 1/16 x 640 = 40 seedlings

2 PPRR' - large leaves, pink flower = 2/16 x 640 = 80 seedlings

2 PP'RR - medium leaves, red flower = 2/16 x 640 = 80 seedlings

4 PP'RR' - medium leaves, pink flower = 4/16 x 640 = 160 seedlings

1 PPR'R' - large leaves, white flower = 1/16 x 640 = 40 seedlings

2 PP'R'R' - medium leaves, white flower = 2/16 x 640 = 80 seedlings

1 P'P'RR - small leaves, red flower = 1/16 x 640 = 40 seedlings

2 P'P'RR' - small leaves, pink flower = 2/16 x 640 = 80 seedlings

1 P'P'R'R' = small leaves, white flower = 1/16 x 640 = 40 seedlings

After a polypeptide chain has been synthesized, certain amino acids in the peptide may become modified. For each modified amino acid, identify the standard amino acid from which it is derived. Enter the unabbreviated name of the standard amino acid.

Answers

Answer:

Lysine

Explanation:

Lysine is a unabbreviated name of amino acid. It is used in biosynthesis of proteins. It contains [tex]\alpha[/tex]-amino group and [tex]\alpha[/tex]-carboxylic acid group which has formula is C6H14N2O2. Lysine is also considered as building block of amino acid. It is used for treating cold sores and can be applied directly to the skin.

Disscuse 2 causes and 2 effects of deforestation.

Answers

causes:
1. the increase in population and growth of the human race
2. the need for housing and industrial advancements

effects:
1. loss of habitat for wildlife
2 loss of trees for oxygen

The only part of the earths inner structure that is a liquid is the

Answers

Answer:

The answer would be the outer core

Explanation:

Which are examples of active transport across the cell membrane? a. osmosis and diffusion b. diffusion and facilitated diffusion c. osmosis and chemiosmosis d. endocytosis and exocytosis

Answers

Answer:

d. endocytosis and exocytosis

Explanation:

These processes bring specific items in/out of the cell through active transport since the particles being brought in are generally large. Water for example, a much smaller particle, would use passive transport through the process of osmosis. Hope this helps!

Endocytosis and exocytosis are examples of active transport across the cell membrane.

Active transport is the movement of substances in and out of the cell through the membrane using energy and occurs against a concentration gradient.

Endocytosis is called the process by which cells incorporate into them molecules, large or small, that cannot pass through the cell membrane.

An example is the endocytosis of the complex that is formed between receptor proteins of polypeptide or protein hormones at the level of the plasma membrane.

Exocytosis is the process by which different types of molecules contained in a cytoplasmic vesicle of a cell are secreted outwards.

Insulin secretion is done in small pinocytosic vesicles that have insulin in colloidal dispersion, this secretion is in favor of a gradient, since insulin is more concentrated within the cell than in the extracellular space.

Therefore, we can conclude that endocytosis and exocytosis are examples of active transport across the cell membrane.

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II. PARTS OF THE DIGESTIVE TRACT A. ORAL CAVITY After ingestion, the physical breakdown of solid foods (mechanical digestion) begins in the oral cavity (mouth). Describe how food is mechanically digested in the oral cavity. Include a discussion of how the teeth, tongue, and saliva work together to convert solid food into a moist, semi-solid mass of food called a bolus. Example: think of how a hard, dry saltine cracker is converted into a moist ball (bolus) in the mouth. B. PHARYNX and ESOPHAGUS 1. After food has been mechanically digested, mixed with saliva, and a bolus has formed, it is swallowed. Swallowing moves the bolus from the mouth into the esophagus. Discuss the events that occur during swallowing. 2. Which portions of the pharynx does food pass through when swallowing

Answers

Answer:

This begins with the gradual breaking down of the food in the mouth, by grinding the food substances with the teeth this is mastication, and the secretion of saliva, which moisten the food, soften it so that the salivary amylase enzyme, carried out the mechanical digestion.

Swallowing is a wavelike muscular contraction which involve the contraction of the longitudinal and circular muscles of the oesophagus, which pushes the bolus down  to the stomach.

The food pass  Oropharynx. While the epiglottis prevents the bolus from entering the trachea.

This is followed by the rolling  up of the tongue, the pushing the broken down food now chyme towards the back of the mouth, pressing it against the soft palate. At this stage a bolus is formed.From here it is pushed into the throat,where it is pushed down the oesophagus by peristalsis.

Explanation:

g B. PROTEINS 1. Name the gastric enzyme that initiates protein digestion. Explain how this enzyme is activated. Pepsin is the gastric enzyme that initiates protein digestion. It is activated by stomach acid into the active form. It then breaks down the protein in our food into smaller particles like peptide fragments and amino acids. 2. Name the ducts in the pathway by which pancreatic juice flows from the pancreas to the duodenum. The Pancreatic duct. 3. Describe 3 ways the body uses these amino acids..

Answers

Answer:

1-the gastric enzyme is pepsin, which is why it is a peptidase, since it catalyzes the binding of proteins within the stomach. Its activation method is the acidic pH of the stomach.

2-Pancreatic juice is a juice that hydrolyzes and helps the digestion of proteins or peptides, since this is the EXOCRINE substance of the pancreas, this juice being exocrine is poured into the main pancreatic duct of the pancreas and then through the choledochol in the blister of toilet at intestinal level.

3-amino acids are used by the body for hormonal, transport, and structural purposes. It also has other functions such as the conformation of the same DNA, but there are 3 that must be answered.

Explanation:

Proteins have structures or junctions that are quaternary, tertiary, binary, and primary.

the easiest to degrade with the quaternary and tertiary while the other two do not.

It is important that you know this fact why these structures are ordered from the outside to the inside or inside the protein, the outermost ones are the quaternary ones and the innermost ones are the primary ones.

A protein ceases to be protein and becomes free and separated amino acids when it reaches the heart of the protein and breaks the primary bond, or the sea the strongest and most difficult to break.

These amino acids have multiple functions but they can be said which, when united, are the unit that makes up proteins or peptides.

Hitchhiker's thumb is inherited via two recessive alleles and causes a hyperextensibility of the thumb. The dominant allele causes a straight thumb phenotype. Predict the phenotypic and genotypic ratios from the following cross.

One parent with Hitchhiker's thumb crossed with a Straight thumbed individual who had a parent with Hitchhiker's thumb.

a. Phenotypic and Genotypic 1:1
b. Phenotypic 2:1 and Genotypic 1:1
c. Phenotypic 1:1 and Genotypic 2:1
d. Phenotypic and Genotypic 3:1

Answers

Answer:

a. Phenotypic and Genotypic 1:1

Explanation:

Two recessive alleles are required in order to be phenotypically affected for Hitchhiker's thumb. Hence, the genotype of the parent with Hitchhiker's thumb would be homozygous recessive.

Assuming the trait to be represented by the allele h, the genotype of the parent with Hitchhiker's thumb would be hh while the genotype of an individual with straight thumb who had a parent with Hitchhiker's thumb would be heterozygous, Hh.

Crossing the two individuals.

                        hh   x   Hh

Progeny:     Hh    hh    Hh    hh

Hh - Straight thumb

hh - Hitchhiker's thumb

Hence, the genotypic ratio is 1:1 while the phenotypic ratio is also 1:1.

The correct option is a.

Consider an experiment where you digest a DNA molecule with restriction enzyme BclI. You resolve the products of the digest by gel electrophoresis. Then, you cut out each of the resulting two bands from the gel and sequence the DNA. The sequencing results return two DNA segments.
Segment 1
5′ CCGCGGT 3′
3′ GGCGCCACTAG 5′
Segment 2
5′ GATCAGGATCC 3′
3′ TCCTAGG 5′
1. What is the sequence of the BclI recognition site?
2. What type of ends do the products have?

Answers

Answer:

This BclI restriction enzyme recognizes and cut at T / CTAG nucleotide sequences.

Explanation:

5′ CCGCGGT 3′

3′ GGCGCCACTAG 5′

Segment 2

5′ GATCAGGATCC 3′

3′            TCCTAGG 5′

The BclI enzyme generates sticky ends, it means that the enzyme recognises and cuts nucleotide sequences without complementary bases, which also have weak hydrogen bonds. The sticky ends are then generated when an enzyme produces unpaired nucleotide ends. Nonetheless, restriction enzymes generally produce blunt ends, i.e., both strands cut at the same site.

Photon energy is proportional to which of the following?
period of the light wave
frequency of the light wave
speed of the light wave
color of the light wave

PLZ ANSWER 20 POINTS

Answers

Frequency of the light wave

Why does the growth of dodder eventually lead to the death of a host plant?​

Answers

Answer:

it deprives the plant of nutrients

Explanation:

True or False: Cells will generally divide when they're too large​

Answers

Answer:

true

Explanation:

the cell becomes two

Yes, this statement is TRUE cells will generally divide when they're too large

Why do cells divide when they get too big?

The larger a cell becomes, the more demands the cell places on its DNA. If the cell grows too large, it will have trouble moving enough nutrients and wastes across the cell membrane.

When cells will generally divide?

The mitotic phase follows interphase. Mitosis is nuclear division during which duplicated chromosomes are segregated and distributed into daughter nuclei. Usually the cell will divide after mitosis in a process called cytokinesis in which the cytoplasm is divided and two daughter cells are formed.

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Ill mark you as Brainliest and give you points !!!!!

Answers

The first one is B and the second one is B , brainliest would appreciated

Answer:

The independent variable is:

the factor that is changed in an experimentthe change does not depend on other factors

The dependent variable is:

what is going to be affectedwhat is being testedwhat is being observed or measured

Why to use small beads for immobilizing enzymes

Answers

Answer:

Explanation:

Effects of bead size and bead amount on enzyme activity. Beads containing crude enzyme were prepared in the presence of sodium alginate (2% w/v) in CaCl 2 (5% w/v) solution. Each treatment was performed in triplicate.

Solid, gas, and liquid Which states of matter have a set shape? Explain why this is, based on the animation you observe for the different states of matter. Which states of matter have a set volume? Explain this based on the animations you observe for the different states of matter?

Answers

Answer:Solid has a set shape. Solid can move but gas and liquid is more flexible than solid. Solid has a fixed volume while liquid and gas takes the volume of its container. Solid stays in one place while gas and liquid is flexible.

Explanation:

Sleve tubes are found in which vascular tissue?
OA. phloem
OB. xylem
Oc.
tracheids

Answers

Answer:

A. phloem

Explanation:

Chemical equilibrium results if_____.

Answers

Answer:

what he said ^

Explanation:

i think...

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